MOTS-c 10mg Vial | Aura Peptides Official UK

The MOTS-c 10mg Vial by Aura Peptides is a high-purity mitochondrial-derived peptide (MDP) engineered specifically for laboratory research evaluating cellular energy metabolism, insulin sensitivity pathways, and exercise-mimetic metabolic signaling in the UK. Supplied as a vacuum-sealed, lyophilized powder, this 10mg formulation offers researchers optimal sequence stability and precise reconstitution control for quantitative assays.

Every batch of Aura Peptides MOTS-c 10mg undergoes rigorous analytical testing via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to guarantee purity ratings exceeding 98.0%.

Technical Specifications: MOTS-c 10mg Research Vial

Parameter	Technical Specification
Product Identifier	AURA-MOTSC-10V
Active Sequence Content	10 mg lyophilized powder per vial
Physical Appearance	Lyophilized white cake/powder
Sequence	Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Purity Grade	$\ge$98.0% (Verified by HPLC & MS)
CAS Number	1627580-64-6
Molecular Formula	$\text{C}_{101}\text{H}_{152}\text{N}_{28}\text{O}_{22}\text{S}_{2}$
Molecular Weight	~2174.6 g/mol
Storage Parameters	Store un-reconstituted at -20°C; store reconstituted solution at 2°C to 8°C

Key Research Applications of MOTS-c

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a unique 16-amino-acid peptide encoded within the mitochondrial genome rather than the nuclear genome. It is widely investigated in metabolic and longevity research for its signaling functions:

• AMPK Pathway Activation: Studied for its role in directly activating AMP-activated protein kinase (AMPK), a central regulator of cellular energy homeostasis.

• Glucose Regulation & Insulin Sensitivity: Investigated in cellular models for enhancing glucose uptake into skeletal muscle tissue independently of insulin signaling.

• Mitochondrial Flexibility & Aging: Researched for its capacity to translocate to the nucleus during metabolic stress and regulate adaptive nuclear gene expression.

Reconstitution & Laboratory Handling Protocols

To protect the structural integrity of the mitochondrial sequence during laboratory preparation:

1. Temperature Equilibration: Allow the freeze-dried vial to reach room temperature before adding liquid diluent.

2. Diluent Introduction: Gently introduce Bacteriostatic Water or Sterile Saline along the inside glass wall of the vial.

3. Gentle Dissolution: Swirl the vial gently in a circular motion until completely clear. Avoid vigorous shaking, as mechanical agitation can disrupt delicate peptide bonds.

Quality Control & Analytical Documentation

At Aura Peptides Official UK, sequence identity and batch consistency are verified through rigorous analytical protocols:

• HPLC Mass Purity: Confirms single-peak clarity and verifies the absence of truncated synthesis by-products.

• Mass Spectrometry (MS): Confirms the exact molecular mass profile ($\text{MW} \approx 2174.6\text{ g/mol}$) against baseline reference standards.

• Certificates of Analysis (CoAs): Batch-specific CoAs are accessible for verified research users upon request.

Frequently Asked Questions

What makes MOTS-c unique compared to nuclear-encoded peptides?

MOTS-c is a mitochondrial-derived peptide (MDP), meaning its genetic code originates within the mitochondria. It functions as a metabolic signaling molecule capable of communicating cellular energy status between the mitochondria and nucleus.

How should the MOTS-c 10mg vial be stored?

Un-reconstituted freeze-dried vials should be stored frozen at or below -20°C, protected from light exposure. Once reconstituted with sterile diluent, store the solution refrigerated between 2°C and 8°C.

Regulatory Compliance Notice

Laboratory Notice: All products supplied by aurapeptides.uk, including MOTS-c 10mg Vials, are strictly intended for laboratory in vitro research, analytical evaluation, and scientific inquiry. They are not intended for human consumption, clinical administration, medical diagnosis, or therapeutic use.