AHK-Cu 100mg Vial | Aura Peptides Official UK

The AHK-Cu 100mg Vial by Aura Peptides is a high-purity copper tripeptide variant (Ala-His-Lys · Cu²⁺) formulated specifically for hair follicle dynamics, dermal papilla cell culture, and extracellular matrix (ECM) remodeling research in the UK. Supplied as a high-concentration 100mg lyophilized powder, this formulation provides laboratory researchers with extended utility, sequence stability, and volume precision for quantitative assays.

Every batch of Aura Peptides AHK-Cu 100mg is synthesized under stringent analytical standards and independently verified via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to guarantee purity ratings exceeding 98.0%.

Technical Specifications: AHK-Cu 100mg Research Vial

Parameter	Technical Specification
Product Identifier	AURA-AHKCU-100V
Active Sequence Content	100 mg lyophilized powder per vial
Physical Appearance	Distinctive blue lyophilized cake
Sequence	Ala-His-Lys · Cu²⁺
Purity Grade	$\ge$98.0% (Verified by HPLC & MS)
CAS Number	126828-32-8
Molecular Formula	$\text{C}_{15}\text{H}_{26}\text{N}_{6}\text{O}_{4}\text{Cu}$
Molecular Weight	~417.95 g/mol
Storage Parameters	Store un-reconstituted at -20°C; store reconstituted solution at 2°C to 8°C

Key Research Applications of AHK-Cu

AHK-Cu (Ala-His-Lys copper complex) is an analogue of GHK-Cu in which the N-terminal glycine is substituted with alanine. This subtle modification is widely investigated in dermatological, trichological, and vascular biology research:

• Dermal Papilla Cell Proliferation: Studied for its stimulatory effect on human dermal papilla cells, supporting research into hair follicle growth cycles and anagen phase lengthening.

• Extracellular Matrix (ECM) Synthesis: Researched for promoting type I collagen and elastin expression in dermal fibroblasts, assisting in skin thickness and structural density studies.

• Vascularization Signaling: Evaluated for upregulating vascular endothelial growth factor (VEGF) expression to support microvascular supply in target tissue models.

Reconstitution & Laboratory Handling Protocols

To protect the structural stability of the copper tripeptide complex during reconstitution:

1. Temperature Equilibration: Allow the freeze-dried vial to reach room temperature before adding liquid diluent to avoid thermal stress.

2. Diluent Introduction: Gently introduce Bacteriostatic Water or Sterile Saline along the inside glass wall of the vial rather than directly onto the lyophilized powder.

3. Gentle Dissolution: Swirl the vial in smooth, circular motions until completely clear. Avoid vigorous shaking, as high friction can shear fragile peptide complexes.

Quality Assurance & Certificate of Analysis (CoA)

At Aura Peptides Official UK, sequence integrity and batch consistency are verified through two-tier testing:

• HPLC Mass Purity: Confirms single-peak baseline separation and verifies zero presence of un-complexed copper or synthesis residue.

• Mass Spectrometry (MS): Validates the exact molecular mass identity ($\text{MW} \approx 417.95\text{ g/mol}$) against standard reference profiles.

• Documentation: Batch-specific Certificates of Analysis (CoAs) are accessible for verified research users upon request.

Frequently Asked Questions

What is the difference between AHK-Cu and GHK-Cu?

AHK-Cu uses alanine at its N-terminal position (Ala-His-Lys), whereas GHK-Cu uses glycine (Gly-His-Lys). In laboratory research, AHK-Cu is specifically evaluated for hair follicle dermal papilla signaling and microvascular research.

Why is the AHK-Cu powder blue?

Like GHK-Cu, the blue hue is caused by the coordination complex formed when divalent copper ions ($\text{Cu}^{2+}$) bind tightly to the tripeptide sequence.

How should the 100mg AHK-Cu vial be stored?

Un-reconstituted freeze-dried vials should be stored frozen at or below -20°C in a dark environment. Once reconstituted, store liquid solutions refrigerated between 2°C and 8°C.

Compliance & Regulatory Notice

Laboratory Notice: All products supplied by aurapeptides.uk, including AHK-Cu 100mg Vials, are strictly intended for laboratory in vitro research, analytical evaluation, and scientific inquiry. They are not intended for human consumption, clinical administration, cosmetic application, or medical diagnosis.